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Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases.
Kartha N, Gianopulos JE, Schrank Z, Cavender SM, Dobersch S, Kynnap BD, Wallace-Povirk A, Wladyka CL, Santana JF, Kim JC, Yu A, Bridgwater CM, Fuchs K, Dysinger S, Lampano AE, Notta F, Price DH, Hsieh AC, Hingorani SR, Kugel S. Kartha N, et al. Among authors: santana jf. Sci Transl Med. 2023 May 3;15(694):eabn9674. doi: 10.1126/scitranslmed.abn9674. Epub 2023 May 3. Sci Transl Med. 2023. PMID: 37134154 Free PMC article.
Nuclear export restricts Gdown1 to a mitotic function.
Ball CB, Parida M, Santana JF, Spector BM, Suarez GA, Price DH. Ball CB, et al. Among authors: santana jf. Nucleic Acids Res. 2022 Feb 28;50(4):1908-1926. doi: 10.1093/nar/gkac015. Nucleic Acids Res. 2022. PMID: 35048979 Free PMC article.
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation.
Mullen NJ, Shukla SK, Thakur R, Kollala SS, Wang D, Chaika N, Santana JF, Miklavcic WR, LaBreck DA, Mallareddy JR, Price DH, Natarajan A, Mehla K, Sykes DB, Hollingsworth MA, Singh PK. Mullen NJ, et al. Among authors: santana jf. bioRxiv [Preprint]. 2024 Jan 13:2023.04.03.535399. doi: 10.1101/2023.04.03.535399. bioRxiv. 2024. PMID: 37066260 Free PMC article. Preprint.
TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.
Seberg HE, Van Otterloo E, Loftus SK, Liu H, Bonde G, Sompallae R, Gildea DE, Santana JF, Manak JR, Pavan WJ, Williams T, Cornell RA. Seberg HE, et al. Among authors: santana jf. PLoS Genet. 2017 Mar 1;13(3):e1006636. doi: 10.1371/journal.pgen.1006636. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28249010 Free PMC article.